The three chemical mutagens were mitomycin C ( MMC, DNA crosslinker), bleomycin ( BLM, radiometric agent), methyl methanesulfonate ( MMS, alkylating agent). 3种化学诱变剂是丝裂霉素C(MMC,DNA交联剂)、博来霉素(BLM,似X线剂)、甲基甲烷磺酸酯(MMS,烷化剂)。
Cellular response to DNA damage caused by methyl methanesulfonate ( MMS) in human senescent diploid fibroblasts 人衰老二倍体成纤维细胞对烷化剂损伤的应答
The Effects of Methyl Methanesulfonate on Chromosome Aberration of Mouse Sperm 甲磺酸甲酯对小鼠精子染色体畸变的影响
Objective To explore the cellular response of human senescent diploid fibroblasts ( 2BS) to the DNA damage caused by methyl methanesulfonate ( MMS). 目的观察衰老的人胚肺二倍体成纤维细胞(2BS)对烷化剂甲磺酸甲酯(MMS)诱导的DNA损伤的应答。
On above results, TbL sensitively and fleetly gives instant luminescence response to the depurination of DNA caused by Methyl methanesulfonate ( MMS) and acidic conditions. 基于上述实验结果,TbL能够选择性的对甲基磺酸甲酯(MMS)以及酸性条件造成的DNA脱嘌呤给出快速、灵敏的荧光响应。